The study appraised the effects of investments in telecommunication infrastructure on economic growth of Nigeria measured by gross domestic product using a comprehensive national level data set in Nigeria for a sample period of 16 years (1992-2007). Data on economic variables such as gross domestic product, government expenditure were obtained from the Statistical Bulletin published by Central Bank of Nigeria. Data on telecommunication infrastructure investment such as telephone mainlines (both fixed line and mobile), total capital expenditure, telecom sector revenue and telecom sector employment were sourced from the publication of the International Telecommunication Union , the Nigeria Communication Commission and as well as World Bank Development Indicator Database. The data were analyzed through the pooled ordinary least squared (OLS) regression methods. The causal relationship between the likely interdependence of telecommunication and economic variables were tested using the time series data. The results showed that telecommunication infrastructure measured by teledensity and telecommunication employment is both statistically significant and positively correlated with economic growth. The study concluded that the stock of telecommunication infrastructure plays a role in determining growth and productivity in Nigeria and that there is the need to create a conducive and competitive climate for the growth of the telecommunication industry, encourage more investment in the sector through private participation, stable and transparent telecommunication policies so that the capital required for building telecommunication infrastructure can be met.