The marauding of ethno-religion cleavages have become the pervading situations in all corners in Nigeria political system to the extent that hat has grown, it are killing the political development in Nigeria. This has a serious impact on peaceful human co-existence, leadership composition opportunity, ethnic domination, inequality, and party formations, among other things. The study investigates the impact of ethno-religious cleavages in Nigeria. The totality of menace arising from these ethno-religious, tribal and ethnic development of communities against one another limit one of the central states. The paper used content analysis to explore the impacts of combined factors of ethno-religion cleavages on development. The paper recommended among others that the paper explored various ethnic and religious cleavages in Nigeria for peaceful human co-existence.